Visual changes in a patient treated with clomiphene citrate for ovarian stimulation: case report

Authors

  • Kamilla Monteiro Plácido
  • Mariana Fonseca Roller Barcelos
  • Natalia Ivet Zavattiero Tierno
  • Leilane Gabriele Noleto Lima

DOI:

https://doi.org/10.51723/hrj.v5i25.1068

Keywords:

Clomifeno. Fertilização in vitro. Indução da ovulação. Reprodução

Abstract

Objective: To describe a case of a 39-year-old patient undergoing assisted reproduction who presented visual changes that began after two days of using clomiphene citrate. Method: Observational and descriptive study, of the case report type, about a patient who presented side effects after starting clomiphene citrate for ovarian stimulation. Result:Clomiphene citrate is often used as a treatment in ovulatory and anovulatory women. Like any drug, it can have side effects and visual changes are the least common among them. Conclusion: Visual disturbances experienced by a small percentage while using the medication can represent a serious complication for the patient.

References

Greenblatt RB, Barfield WE, Jungck CE, Raio AW. Indução da ovulação com MRL/41. Relatório preliminar. JAMA. 1961; 178: 101-104

Taylor HS, Fritz MA, Lubna Pal, Emre Seli. Speroff’s clinical gynecologic endocrinology and infertility. Philadelphia: Wolters Kluwer; 2020.

Racette L, Casson PR, Claman P, Zackon DH, Casson EJ. An investigation of the visual disturbances experienced by patients on clomiphene citrate. Fertility and Sterility. 2010 Mar;93(4):1169–72.

Russom M, Pradeep B, Zeregabr M, Fessehatzion K, Araya N. Cegueira e distúrbio retiniano associado ao citrato de clomifeno: avaliação de série de casos. Clin Med Invest 2017; 2: 1–4

Brasil, Ministério da Saúde. Carta Circular nº 166/2018-CONEP/SECNS/MS – Esclarecimentos acerca da tramitação dos estudos do tipo “relato de caso” no Sistema CEP/Conep para a área biomédica. Brasília, DF. 2018. Disponível em: http://conselho.saude.gov.br/images/comissoes/conep/documentos/CARTAS/CartaCircular166.pdf

Guideline of the European Society of Human Reproduction and Embryology.Ovarian Stimulation for IVF/ICSI. 2019. Disponível em: https://www.eshre.eu/Guidelines-and-Legal/Guidelines/Ovarian-Stimulation-in-IVF-ICSI

Racette L, Casson PR, Claman P, Zackon DH, Casson EJ. An investigation of the visual disturbances experienced by patients on clomiphene citrate. Fertility and Sterility. 2010 Mar;93(4):1169–72.

Alizadeh Y, Moravvej Z, Khakpour Y, Azaripour E, Akbari M, Soltani-Moghadam R. Presumed clomiphene-induced optic neuropathy: A case report. International Journal of Reproductive BioMedicine (IJRM). 2021 Jun 23.

Additional Files

Published

2024-08-30

How to Cite

Monteiro Plácido, K. ., Fonseca Roller Barcelos, M. ., Zavattiero Tierno, N. I., & Noleto Lima, L. G. . (2024). Visual changes in a patient treated with clomiphene citrate for ovarian stimulation: case report. Health Residencies Journal, 5(25). https://doi.org/10.51723/hrj.v5i25.1068

Issue

Vol. 5 No. 25 (2024): Educação em Saúde Pública: um saber fundamental para o SUS

Section

Relato de caso

License

Copyright (c) 2024 Kamilla Monteiro Plácido, Mariana Fonseca Roller Barcelos, Natalia Ivet Zavattiero Tierno, Leilane Gabriele Noleto Lima

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