GUILLAIN-BARRÉ SYNDROME IN A YOUNG PATIENT WITH ATYPICAL PRESENTATION: CASE REPORT

Authors

  • Matheus Catão Tsugami HRS
  • Dilson Palhares Ferreira
  • Sophia Ambrosio Palhares

DOI:

https://doi.org/10.51723/hrj.v5i22.969

Keywords:

Síndrome de Guillain-Barré. Atípico. Fraqueza ascendente. Imunoglobulina

Abstract

Guillain-Barré syndrome (GBS) is an autoimmune disease of the peripheral nervous system. Characterized by an ascending and symmetrical paralysis, associated with areflexia or hyporeflexia. The case report concerns a 16-year-old male patient. Admitted to the Hospital Regional de Sobradinho in the Federal District (HRS), he presented motor impairment in the lower and upper limbs for four days, progressing to dysarthria and dysphagia for two days, and report of suspected upper airway infection for around 3 weeks. prior to symptoms. During hospitalization, a lumbar puncture was performed on the patient and 10 ml of cerebrospinal fluid (CSF) was removed, with proteinorrhachia (473 protein) and absence of leukocytes (0), with no changes in bacterioscopy, cultures, Genexpert, fungi, in the VDRL, characterizing a protein-cellular dissociation. Electroneuromyography of the upper limbs was performed in favor of GBS. The patient was treated with intravenous immunoglobulin with clinical improvement and was discharged with referral for motor rehabilitation. This is a presentation of GBS in a young patient, with a severe form due to the evolution of muscle weakness and symptoms of dysphagia with a good therapeutic response to immunoglobulin.

 Keywords: Guillain-Barré syndrome. Atypical. Rising weakness. Immunoglobulin.

References

Carvalho BTC et al. Consenso sobre o uso de IgIV em pacientes com IDP. Rev. bras. alerg. imunopatol. V. 33, n. 3, 2010

Costa ACD da. Síndrome de Guillain-Barré: uma revisão integrativa de literatura e de dados do Sistema Único de Saúde. Tese (Graduação em Gestão de Saúde Coletiva) – Faculdade de Ciências da Saúde, Universidade de Brasília. Brasília, p.8. 2016

Fluxograma de Investigação Laboratorial das Hepatites Virais na Atenção Básica – elaborado por um grupo de profissionais das SMS de Londrina, Cambé, Rolândia e Ibiporã, da 17a Regional de Saúde e do CISMEPAR, conforme o PNHV/MS e o LACEN-PR Londrina, abril 2010

Mccombe PA et al. Sex differences in Guillain Barré syndrome, chronic inflammatory demyelinating polyradiculoneuropathy and experimental autoimmune neuritis. Front Immunol. 2022

Wachira VK et al . Incidence of Guillain-Barré syndrome in the world between 1985 and 2020: A systematic review. Glob Epidemiol. 2023

Wei DSJ. Severe Guillain-Barré syndrome associated with chronic hepatitis B: A case report and literature review. Medicine (Baltimore). 2021

Published

2024-02-27

How to Cite

Catão Tsugami, M. ., Palhares Ferreira , D., & Ambrosio Palhares, S. (2024). GUILLAIN-BARRÉ SYNDROME IN A YOUNG PATIENT WITH ATYPICAL PRESENTATION: CASE REPORT. Health Residencies Journal - HRJ, 5(22). https://doi.org/10.51723/hrj.v5i22.969